Though the machine garnered some attention at launch (mainly due to the low price point for the machine and its games, which many felt might enable it to make inroads into Nintendo's market share) it was ultimately unsuccessful in unseating the Game Boy from its position as the world's most popular handheld. Reasons commonly cited are the poor quality screen which was prone to blurring and made following the action difficult, a general lack of games and the simplistic nature of those that were released.

Yet another problem was that most of the games that were available were developed in Taiwan or Hong Kong, meaning that fans of big-name Western and Japanese developers were underwhelmed by the apparent lack of support from these companies. Only a tiny handful of games were developed by third parties, including Sachen and the British developer B.I.T.S.. Up against Nintendo's list of popular franchises (Zelda, Mario, Metroid) and those of its third parties (Castlevania, Mega Man) - all of which eventually surfaced on the Game Boy - the Supervision's games were of little interest to most.